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Interaction between IGFBP7 and insulin: a theoretical and experimental study

Insulin-like growth factor binding protein 7 (IGFBP7) can bind to insulin with high affinity which inhibits the early steps of insulin action. Lack of recognition mechanism impairs our understanding of insulin regulation before it binds to insulin receptor. Here we combine computational simulations...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Ruan, Wenjing, Kang, Zhengzhong, Li, Youzhao, Sun, Tianyang, Wang, Lipei, Liang, Lijun, Lai, Maode, Wu, Tao
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4840315/
https://ncbi.nlm.nih.gov/pubmed/27101796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19586
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