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Genotoxicity of flubendazole and its metabolites in vitro and the impact of a new formulation on in vivo aneugenicity
The anti-parasitic benzimidazole flubendazole has been used for many years to treat intestinal infections in humans and animals. Previous genotoxicity studies have shown that the compound is not a bacterial mutagen and a bone marrow micronucleus test, using a formulation that limited systemic absorp...
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| Published in: | Mutagenesis |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4840262/ https://ncbi.nlm.nih.gov/pubmed/26443851 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/mutage/gev070 |
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