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Persistent HCV replication despite priming of functional CD8+ T cells by combined therapy with a vaccine and direct acting antiviral
Exhaustion of antiviral CD8+ T cells contributes to persistence of hepatitis C virus infection. This immune response has proved difficult to restore by therapeutic vaccination, even when HCV replication is suppressed using antiviral regimens containing type I interferon (IFN). Because immunomodulato...
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| 發表在: | Hepatology |
|---|---|
| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4840073/ https://ncbi.nlm.nih.gov/pubmed/26513111 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.28309 |
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