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Attitudes toward prevention of mtDNA-related diseases through oocyte mitochondrial replacement therapy

STUDY QUESTION: Among women who carry pathogenic mitochondrial DNA (mtDNA) point mutations and healthy oocyte donors, what are the levels of support for developing oocyte mitochondrial replacement therapy (OMRT) to prevent transmission of mtDNA mutations? SUMMARY ANSWER: The majority of mtDNA carrie...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Hum Reprod
Hauptverfasser: Engelstad, Kristin, Sklerov, Miriam, Kriger, Joshua, Sanford, Alexandra, Grier, Johnston, Ash, Daniel, Egli, Dieter, DiMauro, Salvatore, Thompson, John L.P., Sauer, Mark V., Hirano, Michio
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4840023/
https://ncbi.nlm.nih.gov/pubmed/26936885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/humrep/dew033
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