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Dystrophin expression in muscle stem cells regulates their polarity and asymmetric division
Dystrophin is expressed in differentiated myofibers where it is required for sarcolemmal integrity, and loss-of-function mutations in its gene result in Duchenne Muscular Dystrophy (DMD), a disease characterized by progressive and severe skeletal muscle degeneration. Here we found that dystrophin is...
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| Veröffentlicht in: | Nat Med |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4839960/ https://ncbi.nlm.nih.gov/pubmed/26569381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3990 |
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