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Wnt7a stimulates myogenic stem cell motility and engraftment resulting in improved muscle strength

Wnt7a/Fzd7 signaling stimulates skeletal muscle growth and repair by inducing the symmetric expansion of satellite stem cells through the planar cell polarity pathway and by activating the Akt/mTOR growth pathway in muscle fibers. Here we describe a third level of activity where Wnt7a/Fzd7 increases...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Bentzinger, C. Florian, von Maltzahn, Julia, Dumont, Nicolas A., Stark, Danny A., Wang, Yu Xin, Nhan, Kevin, Frenette, Jérôme, Cornelison, DDW, Rudnicki, Michael A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Rockefeller University Press 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3987134/
https://ncbi.nlm.nih.gov/pubmed/24711502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201310035
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