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Wnt7a stimulates myogenic stem cell motility and engraftment resulting in improved muscle strength
Wnt7a/Fzd7 signaling stimulates skeletal muscle growth and repair by inducing the symmetric expansion of satellite stem cells through the planar cell polarity pathway and by activating the Akt/mTOR growth pathway in muscle fibers. Here we describe a third level of activity where Wnt7a/Fzd7 increases...
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| Main Authors: | , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The Rockefeller University Press
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3987134/ https://ncbi.nlm.nih.gov/pubmed/24711502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201310035 |
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