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In Vitro Polarization of Colonoids to Create an Intestinal Stem Cell Compartment

The polarity of proliferative and differentiated cellular compartments of colonic crypts is believed to be specified by gradients of key mitogens and morphogens. Indirect evidence demonstrates a tight correlation between Wnt- pathway activity and the basal-luminal patterning; however, to date there...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Attayek, Peter J., Ahmad, Asad A., Wang, Yuli, Williamson, Ian, Sims, Christopher E., Magness, Scott T., Allbritton, Nancy L.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4839657/
https://ncbi.nlm.nih.gov/pubmed/27100890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0153795
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