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In Vitro Polarization of Colonoids to Create an Intestinal Stem Cell Compartment

The polarity of proliferative and differentiated cellular compartments of colonic crypts is believed to be specified by gradients of key mitogens and morphogens. Indirect evidence demonstrates a tight correlation between Wnt- pathway activity and the basal-luminal patterning; however, to date there...

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Pubblicato in:PLoS One
Autori principali: Attayek, Peter J., Ahmad, Asad A., Wang, Yuli, Williamson, Ian, Sims, Christopher E., Magness, Scott T., Allbritton, Nancy L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4839657/
https://ncbi.nlm.nih.gov/pubmed/27100890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0153795
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