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Formation of arrays of planar, murine, intestinal crypts possessing a stem/proliferative cell compartment and differentiated cell zone

A simple, in vitro intestinal model recapitulating key aspects of crypt architecture and physiology would facilitate our understanding the impact of drugs, foods and microbial metabolites on the intestine. To address the limitations of previously reported intestinal in vitro platforms, we developed...

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Detalhes bibliográficos
Publicado no:Lab Chip
Main Authors: Kim, Raehyun, Wang, Yuli, Hwang, Shee-Hwan J., Attayek, Peter J., Smiddy, Nicole M., Reed, Mark I., Sims, Christopher E., Allbritton, Nancy L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6337012/
https://ncbi.nlm.nih.gov/pubmed/29944153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8lc00332g
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