Nanoparticle Surface Charge Impacts Distribution, Uptake and Lymph Node Trafficking by Pulmonary Antigen-Presenting Cells

Engineered nanoparticles have the potential to expand the breadth of pulmonary therapeutics, especially as respiratory vaccines. Notably, cationic nanoparticles have been demonstrated to produce superior local immune responses following pulmonary delivery; however, the cellular mechanisms of this in...

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Détails bibliographiques
Publié dans:Nanomedicine
Auteurs principaux: Fromen, Catherine A., Rahhal, Tojan B., Robbins, Gregory R., Kai, Marc P., Shen, Tammy W., Luft, J. Christopher, DeSimone, Joseph M.
Format: Artigo
Langue:Inglês
Publié: 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4839472/
https://ncbi.nlm.nih.gov/pubmed/26656533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2015.11.002
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