Critical Size Limit of Biodegradable Nanoparticles for Enhanced Lymph Node Trafficking and Paracortex Penetration

Lymph node (LN) targeting through interstitial drainage of nanoparticles (NPs) is an attractive strategy to stimulate a potent immune response, as LNs are the primary site for lymphocyte priming by antigen presenting cells (APCs) and triggering of an adaptive immune response. NP size has been shown...

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Veröffentlicht in:Nano Res
Hauptverfasser: Howard, Gregory P., Verma, Garima, Ke, Xiyu, Thayer, Winter M., Hamerly, Timothy, Baxter, Victoria K., Lee, John E., Dinglasan, Rhoel R., Mao, Hai-Quan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7747954/
https://ncbi.nlm.nih.gov/pubmed/33343832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12274-019-2301-3
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