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Nanoparticle Surface Charge Impacts Distribution, Uptake and Lymph Node Trafficking by Pulmonary Antigen-Presenting Cells

Engineered nanoparticles have the potential to expand the breadth of pulmonary therapeutics, especially as respiratory vaccines. Notably, cationic nanoparticles have been demonstrated to produce superior local immune responses following pulmonary delivery; however, the cellular mechanisms of this in...

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Detalhes bibliográficos
Publicado no:Nanomedicine
Main Authors: Fromen, Catherine A., Rahhal, Tojan B., Robbins, Gregory R., Kai, Marc P., Shen, Tammy W., Luft, J. Christopher, DeSimone, Joseph M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4839472/
https://ncbi.nlm.nih.gov/pubmed/26656533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2015.11.002
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