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Mixing and matching TREK/TRAAK subunits generate heterodimeric K(2P) channels with unique properties

The tandem of pore domain in a weak inwardly rectifying K(+) channel (Twik)-related acid-arachidonic activated K(+) channel (TRAAK) and Twik-related K(+) channels (TREK) 1 and TREK2 are active as homodimers gated by stretch, fatty acids, pH, and G protein-coupled receptors. These two-pore domain pot...

詳細記述

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Blin, Sandy, Ben Soussia, Ismail, Kim, Eun-Jin, Brau, Frédéric, Kang, Dawon, Lesage, Florian, Bichet, Delphine
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4839434/
https://ncbi.nlm.nih.gov/pubmed/27035965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1522748113
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