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Tandem Pore Domain Halothane-inhibited K(+) Channel Subunits THIK1 and THIK2 Assemble and Form Active Channels
Despite a high level of sequence homology, tandem pore domain halothane-inhibited K(+) channel 1 (THIK1) produces background K(+) currents, whereas THIK2 is silent. This lack of activity is due to a unique combination of intracellular retention and weak basal activity in the plasma membrane. Here, w...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4192476/ https://ncbi.nlm.nih.gov/pubmed/25148687 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.600437 |
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