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Anabolic actions of Notch on mature bone

Notch controls skeletogenesis, but its role in the remodeling of adult bone remains conflicting. In mature mice, the skeleton can become osteopenic or osteosclerotic depending on the time point at which Notch is activated or inactivated. Using adult EGFP reporter mice, we find that Notch expression...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Liu, Peng, Ping, Yilin, Ma, Meng, Zhang, Demao, Liu, Connie, Zaidi, Samir, Gao, Song, Ji, Yaoting, Lou, Feng, Yu, Fanyuan, Lu, Ping, Stachnik, Agnes, Bai, Mingru, Wei, Chengguo, Zhang, Liaoran, Wang, Ke, Chen, Rong, New, Maria I., Rowe, David W., Yuen, Tony, Sun, Li, Zaidi, Mone
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4839423/
https://ncbi.nlm.nih.gov/pubmed/27036007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1603399113
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