Anabolic actions of Notch on mature bone

Notch controls skeletogenesis, but its role in the remodeling of adult bone remains conflicting. In mature mice, the skeleton can become osteopenic or osteosclerotic depending on the time point at which Notch is activated or inactivated. Using adult EGFP reporter mice, we find that Notch expression...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Liu, Peng, Ping, Yilin, Ma, Meng, Zhang, Demao, Liu, Connie, Zaidi, Samir, Gao, Song, Ji, Yaoting, Lou, Feng, Yu, Fanyuan, Lu, Ping, Stachnik, Agnes, Bai, Mingru, Wei, Chengguo, Zhang, Liaoran, Wang, Ke, Chen, Rong, New, Maria I., Rowe, David W., Yuen, Tony, Sun, Li, Zaidi, Mone
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2016
Assuntos:
PNAS Plus
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4839423/
https://ncbi.nlm.nih.gov/pubmed/27036007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1603399113
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