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Sclerostin influences body composition by regulating catabolic and anabolic metabolism in adipocytes
Sclerostin has traditionally been thought of as a local inhibitor of bone acquisition that antagonizes the profound osteoanabolic capacity of activated Wnt/β-catenin signaling, but serum sclerostin levels in humans exhibit a correlation with impairments in several metabolic parameters. These data, t...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5748171/ https://ncbi.nlm.nih.gov/pubmed/29229807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1707876115 |
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