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Reversal of phenotypes in MECP2 duplication mice using genetic rescue or antisense oligos
Copy number variations have been frequently associated with developmental delay, intellectual disability, and autism spectrum disorders(1). MECP2 duplication syndrome is one of the most common genomic rearrangements in males(2) and is characterized by autism, intellectual disability, motor dysfuncti...
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| Publicado no: | Nature |
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| Principais autores: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4839300/ https://ncbi.nlm.nih.gov/pubmed/26605526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature16159 |
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