Proinsulin and heat shock protein 90 as biomarkers of beta-cell stress in the early period after onset of type 1 diabetes

Rapid evaluation of therapies designed to preserve β cells in persons with type 1 diabetes (T1D) is hampered by limited availability of sensitive β-cell health biomarkers. In particular, biomarkers elucidating the presence and degree of β-cell stress are needed. We characterized β-cell secretory act...

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Bibliographic Details
Published in:Transl Res
Main Authors: WATKINS, RENECIA A., EVANS-MOLINA, CARMELLA, TERRELL, JENNIFER K., DAY, KATHLEEN H., GUINDON, LYNETTE, RESTREPO, IVAN A., MIRMIRA, RAGHAVENDRA G., BLUM, JANICE S., DIMEGLIO, LINDA A.
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4839287/
https://ncbi.nlm.nih.gov/pubmed/26397425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trsl.2015.08.010
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