Heme oxygenase-1 regulates mitochondrial quality control in the heart

The cardioprotective inducible enzyme heme oxygenase-1 (HO-1) degrades prooxidant heme into equimolar quantities of carbon monoxide, biliverdin, and iron. We hypothesized that HO-1 mediates cardiac protection, at least in part, by regulating mitochondrial quality control. We treated WT and HO-1 tran...

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Bibliografski detalji
Izdano u:JCI Insight
Glavni autori: Hull, Travis D., Boddu, Ravindra, Guo, Lingling, Tisher, Cornelia C., Traylor, Amie M., Patel, Bindiya, Joseph, Reny, Prabhu, Sumanth D., Suliman, Hagir B., Piantadosi, Claude A., Agarwal, Anupam, George, James F.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2016
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4838906/
https://ncbi.nlm.nih.gov/pubmed/27110594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.85817
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