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Constrained evolvability of interferon suppression in an RNA virus

Innate immunity responses controlled by interferon (IFN) are believed to constitute a major selective pressure shaping viral evolution. Viruses encode a variety of IFN suppressors, but these are often multifunctional proteins that also play essential roles in other steps of the viral infection cycle...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Garijo, Raquel, Cuevas, José M., Briz, Álvaro, Sanjuán, Rafael
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4838867/
https://ncbi.nlm.nih.gov/pubmed/27098004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24722
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