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Single-Cell Analysis of RNA Virus Infection Identifies Multiple Genetically Diverse Viral Genomes within Single Infectious Units
Genetic diversity enables a virus to colonize novel hosts, evade immunity, and evolve drug resistance. However, viral diversity is typically assessed at the population level. Given the existence of cell-to-cell variation, it is critical to understand viral genetic structure at the single-cell level....
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Gepubliceerd in: | Cell Host Microbe |
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Hoofdauteurs: | , , , , |
Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
Cell Press
2015
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4617633/ https://ncbi.nlm.nih.gov/pubmed/26468746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2015.09.009 |
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