c-Jun represses the human insulin promoter activity that depends on multiple cAMP response elements.

Glucose is known to increase the cAMP concentration in pancreatic beta cells. To determine the mechanism by which cAMP augments insulin gene expression, we first identified the cAMP response elements (CREs) of the human insulin gene. In DNase I footprint analysis, the bacterially synthesized CRE-bin...

全面介紹

Na minha lista:
書目詳細資料
Main Authors: Inagaki, N, Maekawa, T, Sudo, T, Ishii, S, Seino, Y, Imura, H
格式: Artigo
語言:Inglês
出版: 1992
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC48382/
https://ncbi.nlm.nih.gov/pubmed/1310538
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍