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The endonuclease domain of the LINE-1 ORF2 protein can tolerate multiple mutations
BACKGROUND: Approximately 17 % of the human genome is comprised of the Long INterspersed Element-1 (LINE-1 or L1) retrotransposon, the only currently active autonomous family of retroelements. Though L1 elements have helped to shape mammalian genome evolution over millions of years, L1 activity can...
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| Опубликовано в: : | Mob DNA |
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| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4837594/ https://ncbi.nlm.nih.gov/pubmed/27099633 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13100-016-0064-x |
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