Quantitative assessment of BRAF V600 mutant circulating cell-free tumor DNA as a tool for therapeutic monitoring in metastatic melanoma patients treated with BRAF/MEK inhibitors

BACKGROUND: BRAF V600 mutant circulating cell-free tumor DNA (BRAF V600mut ctDNA) could serve as a specific biomarker in patients with BRAF V600 mutant melanoma. We analyzed the value of BRAF V600mut ctDNA from plasma as a monitoring tool for advanced melanoma patients treated with BRAF/MEK inhibito...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Schreuer, Max, Meersseman, Geert, Van Den Herrewegen, Sari, Jansen, Yanina, Chevolet, Ines, Bott, Ambre, Wilgenhof, Sofie, Seremet, Teofila, Jacobs, Bart, Buyl, Ronald, Maertens, Geert, Neyns, Bart
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4837559/
https://ncbi.nlm.nih.gov/pubmed/27095081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-0852-6
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