Microbial metabolite butyrate facilitates M2 macrophage polarization and function

Metabolites from intestinal microbes modulate the mucosal immune system by regulating the polarization and expansion of T cells. Whether the microbial metabolites influence macrophage polarization, however, is poorly understood. Here, we show that the large bowel microbial fermentation product, buty...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Ji, Jian, Shu, Dingming, Zheng, Mingzhu, Wang, Jie, Luo, Chenglong, Wang, Yan, Guo, Fuyou, Zou, Xian, Lv, Xiaohui, Li, Ying, Liu, Tianfei, Qu, Hao
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4837405/
https://ncbi.nlm.nih.gov/pubmed/27094081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24838
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