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Determinants of rodent longevity in the chaperone-protein degradation network

Proteostasis is an integral component of healthy aging, ensuring maintenance of protein structural and functional integrity with concomitant impact upon health span and longevity. In most metazoans, increasing age is accompanied by a decline in protein quality control resulting in the accrual of dam...

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Detalhes bibliográficos
Publicado no:Cell Stress Chaperones
Main Authors: Rodriguez, Karl A., Valentine, Joseph M., Kramer, David A., Gelfond, Jonathan A., Kristan, Deborah M., Nevo, Eviatar, Buffenstein, Rochelle
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4837185/
https://ncbi.nlm.nih.gov/pubmed/26894765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-016-0672-x
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