Sustained high levels of neuregulin-1 in the longest-lived rodents; a key determinant of rodent longevity

Naked mole-rats (Heterocephalus glaber), the longest-lived rodents, live 7-10 times longer than similarly–sized mice and exhibit normal activities for ~75% of their lives. Little is known about the mechanisms that allow them to delay the aging process and live so long. Neuregulin-1 (NRG-1) signaling...

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Publicado en:Aging Cell
Main Authors: Edrey, Yael H, Casper, Diana, Huchon, Dorothee, Mele, James, Gelfond, Jonathan A, Kristan, Deborah M, Nevo, Eviatar, Buffenstein, Rochelle
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4399559/
https://ncbi.nlm.nih.gov/pubmed/22103690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2011.00772.x
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