Protein stability and resistance to oxidative stress are determinants of longevity in the longest-living rodent, the naked mole-rat

The widely accepted oxidative stress theory of aging postulates that aging results from accumulation of oxidative damage. Surprisingly, data from the longest-living rodent known, naked mole-rats [MRs; mass 35 g; maximum lifespan (MLSP) > 28.3 years], when compared with mice (MLSP 3.5 years) exhib...

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Detalhes bibliográficos
Main Authors: Pérez, Viviana I., Buffenstein, Rochelle, Masamsetti, Venkata, Leonard, Shanique, Salmon, Adam B., Mele, James, Andziak, Blazej, Yang, Ting, Edrey, Yael, Friguet, Bertrand, Ward, Walter, Richardson, Arlan, Chaudhuri, Asish
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651236/
https://ncbi.nlm.nih.gov/pubmed/19223593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0809620106
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