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Positioning the Intracellular Salt Potassium Glutamate in the Hofmeister Series by Chemical Unfolding Studies of NTL9

In vitro, replacing KCl by potassium glutamate (KGlu), the E. coli cytoplasmic salt and osmolyte, stabilizes folded proteins and protein-nucleic acid complexes. To understand the chemical basis for these effects and rank Glu(−) in the Hofmeister anion series for protein unfolding, we quantify and in...

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Vydáno v:Biochemistry
Hlavní autoři: Sengupta, Rituparna, Pantel, Adrian, Cheng, Xian, Shkel, Irina, Peran, Ivan, Stenzoski, Natalie, Raleigh, Daniel P., Record, M. Thomas
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4837102/
https://ncbi.nlm.nih.gov/pubmed/27054379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00173
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