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Why Hofmeister effects of many salts favor protein folding but not DNA helix formation

The majority (∼70%) of surface buried in protein folding is hydrocarbon, whereas in DNA helix formation, the majority (∼65%) of surface buried is relatively polar nitrogen and oxygen. Our previous quantification of salt exclusion from hydrocarbon (C) accessible surface area (ASA) and accumulation at...

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Autors principals: Pegram, Laurel M., Wendorff, Timothy, Erdmann, Robert, Shkel, Irina, Bellissimo, Dana, Felitsky, Daniel J., Record, M. Thomas
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867913/
https://ncbi.nlm.nih.gov/pubmed/20385834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0913376107
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