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Steric trapping reveals a cooperativity network in the intramembrane protease GlpG

Membrane proteins are assembled through balanced interactions among protein, lipids and water. Studying their folding while maintaining the native lipid environment is necessary but challenging. Here we present methods for analyzing key elements in membrane protein folding including thermodynamic st...

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Publicado en:Nat Chem Biol
Autores principales: Guo, Ruiqiong, Gaffney, Kristen, Yang, Zhongyu, Kim, Miyeon, Sungsuwan, Suttipun, Huang, Xuefei, Hubbell, Wayne L., Hong, Heedeok
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4837050/
https://ncbi.nlm.nih.gov/pubmed/26999782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2048
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