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Steric trapping reveals a cooperativity network in the intramembrane protease GlpG

Membrane proteins are assembled through balanced interactions among protein, lipids and water. Studying their folding while maintaining the native lipid environment is necessary but challenging. Here we present methods for analyzing key elements in membrane protein folding including thermodynamic st...

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Detalhes bibliográficos
Publicado no:Nat Chem Biol
Main Authors: Guo, Ruiqiong, Gaffney, Kristen, Yang, Zhongyu, Kim, Miyeon, Sungsuwan, Suttipun, Huang, Xuefei, Hubbell, Wayne L., Hong, Heedeok
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4837050/
https://ncbi.nlm.nih.gov/pubmed/26999782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2048
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