Light Controlled Modulation of Gene Expression by Chemical Optoepigenetic Probes

Epigenetic gene regulation is a dynamic process orchestrated by chromatin-modifying enzymes. Many of these master regulators exert their function through covalent modification of DNA and histone proteins. Aberrant epigenetic processes have been implicated in the pathophysiology of multiple human dis...

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Detalhes bibliográficos
Publicado no:Nat Chem Biol
Main Authors: Reis, Surya A., Ghosh, Balaram, Hendricks, J. Adam, Szantai-Kis, D. Miklos, Törk, Lisa, Ross, Kenneth N., Lamb, Justin, Read-Button, Willis, Zheng, Baixue, Wang, Hongtao, Salthouse, Christopher, Haggarty, Stephen J., Mazitschek, Ralph
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836974/
https://ncbi.nlm.nih.gov/pubmed/26974814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2042
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