High-throughput sequencing of partially edited trypanosome mRNAs reveals barriers to editing progression and evidence for alternative editing

Uridine insertion/deletion RNA editing in kinetoplastids entails the addition and deletion of uridine residues throughout the length of mitochondrial transcripts to generate translatable mRNAs. This complex process requires the coordinated use of several multiprotein complexes as well as the sequent...

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Bibliographic Details
Published in:RNA
Main Authors: Simpson, Rachel M., Bruno, Andrew E., Bard, Jonathan E., Buck, Michael J., Read, Laurie K.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2016
Subjects:
Bioinformatics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836643/
https://ncbi.nlm.nih.gov/pubmed/26908922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.055160.115
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