High-throughput sequencing of partially edited trypanosome mRNAs reveals barriers to editing progression and evidence for alternative editing

Uridine insertion/deletion RNA editing in kinetoplastids entails the addition and deletion of uridine residues throughout the length of mitochondrial transcripts to generate translatable mRNAs. This complex process requires the coordinated use of several multiprotein complexes as well as the sequent...

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Vydáno v:RNA
Hlavní autoři: Simpson, Rachel M., Bruno, Andrew E., Bard, Jonathan E., Buck, Michael J., Read, Laurie K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2016
Témata:
Bioinformatics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836643/
https://ncbi.nlm.nih.gov/pubmed/26908922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.055160.115
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