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High-throughput sequencing of partially edited trypanosome mRNAs reveals barriers to editing progression and evidence for alternative editing

Uridine insertion/deletion RNA editing in kinetoplastids entails the addition and deletion of uridine residues throughout the length of mitochondrial transcripts to generate translatable mRNAs. This complex process requires the coordinated use of several multiprotein complexes as well as the sequent...

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Библиографические подробности
Опубликовано в: :RNA
Главные авторы: Simpson, Rachel M., Bruno, Andrew E., Bard, Jonathan E., Buck, Michael J., Read, Laurie K.
Формат: Artigo
Язык:Inglês
Опубликовано: Cold Spring Harbor Laboratory Press 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836643/
https://ncbi.nlm.nih.gov/pubmed/26908922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.055160.115
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