Microglial priming through the lung–brain axis: the role of air pollution–induced circulating factors

Air pollution is implicated in neurodegenerative disease risk and progression and in microglial activation, but the mechanisms are unknown. In this study, microglia remained activated 24 h after ozone (O(3)) exposure in rats, suggesting a persistent signal from lung to brain. Ex vivo analysis of ser...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Mumaw, Christen L., Levesque, Shannon, McGraw, Constance, Robertson, Sarah, Lucas, Selita, Stafflinger, Jillian E, Campen, Matthew J., Hall, Pamela, Norenberg, Jeffrey P., Anderson, Tamara, Lund, Amie K., McDonald, Jacob D., Ottens, Andrew K., Block, Michelle L.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2016
Assuntos:
Research Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836369/
https://ncbi.nlm.nih.gov/pubmed/26864854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201500047
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