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Microglial priming through the lung–brain axis: the role of air pollution–induced circulating factors

Air pollution is implicated in neurodegenerative disease risk and progression and in microglial activation, but the mechanisms are unknown. In this study, microglia remained activated 24 h after ozone (O(3)) exposure in rats, suggesting a persistent signal from lung to brain. Ex vivo analysis of ser...

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書目詳細資料
發表在:FASEB J
Main Authors: Mumaw, Christen L., Levesque, Shannon, McGraw, Constance, Robertson, Sarah, Lucas, Selita, Stafflinger, Jillian E, Campen, Matthew J., Hall, Pamela, Norenberg, Jeffrey P., Anderson, Tamara, Lund, Amie K., McDonald, Jacob D., Ottens, Andrew K., Block, Michelle L.
格式: Artigo
語言:Inglês
出版: Federation of American Societies for Experimental Biology 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836369/
https://ncbi.nlm.nih.gov/pubmed/26864854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201500047
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