Microglial priming through the lung–brain axis: the role of air pollution–induced circulating factors

Air pollution is implicated in neurodegenerative disease risk and progression and in microglial activation, but the mechanisms are unknown. In this study, microglia remained activated 24 h after ozone (O(3)) exposure in rats, suggesting a persistent signal from lung to brain. Ex vivo analysis of ser...

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Bibliographic Details
Published in:FASEB J
Main Authors: Mumaw, Christen L., Levesque, Shannon, McGraw, Constance, Robertson, Sarah, Lucas, Selita, Stafflinger, Jillian E, Campen, Matthew J., Hall, Pamela, Norenberg, Jeffrey P., Anderson, Tamara, Lund, Amie K., McDonald, Jacob D., Ottens, Andrew K., Block, Michelle L.
Format: Artigo
Language:Inglês
Published: Federation of American Societies for Experimental Biology 2016
Subjects:
Research Communication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836369/
https://ncbi.nlm.nih.gov/pubmed/26864854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201500047
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