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Role of N Terminus-Truncated NS1 Proteins of Influenza A Virus in Inhibiting IRF3 Activation

The NS1 protein encoded by influenza A virus antagonizes the interferon response through various mechanisms, including blocking cellular mRNA maturation by binding the cellular CPSF30 3′ end processing factor and/or suppressing the activation of interferon regulatory factor 3 (IRF3). In the present...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Kuo, Rei-Lin, Li, Li-Hsin, Lin, Sue-Jane, Li, Zong-Hua, Chen, Guang-Wu, Chang, Cheng-Kai, Wang, Yi-Ren, Tam, Ee-Hong, Gong, Yu-Nong, Krug, Robert M., Shih, Shin-Ru
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836362/
https://ncbi.nlm.nih.gov/pubmed/26912617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02843-15
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