Rho-associated kinase signalling and the cancer microenvironment: novel biological implications and therapeutic opportunities

The Rho/ROCK pathway is involved in numerous pivotal cellular processes that have made it an area of intense study in cancer medicine, however, Rho-associated coiled-coil containing protein kinase (ROCK) inhibitors are yet to make an appearance in the clinical cancer setting. Their performance as an...

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Foilsithe in:Expert Rev Mol Med
Main Authors: Chin, Venessa T., Nagrial, Adnan M., Chou, Angela, Biankin, Andrew V., Gill, Anthony J., Timpson, Paul, Pajic, Marina
Formáid: Artigo
Teanga:Inglês
Foilsithe: Cambridge University Press 2015
Ábhair:
Review Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836205/
https://ncbi.nlm.nih.gov/pubmed/26507949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/erm.2015.17
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