Lactobacillus acidophilus stimulates intestinal P-glycoprotein expression via a c-Fos/c-Jun-dependent mechanism in intestinal epithelial cells

Our previous studies showed that Lactobacillus acidophilus (LA) culture supernatant (CS) increased P-glycoprotein [Pgp/multidrug resistance 1 (MDR1)] function, expression, and promoter activity in Caco-2 cells. The current studies were designed to elucidate the molecular mechanisms mediating the sti...

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Bibliographic Details
Published in:Am J Physiol Gastrointest Liver Physiol
Main Authors: Priyamvada, Shubha, Anbazhagan, Arivarasu N., Kumar, Anoop, Soni, Vikas, Alrefai, Waddah A., Gill, Ravinder K., Dudeja, Pradeep K., Saksena, Seema
Format: Artigo
Language:Inglês
Published: American Physiological Society 2016
Subjects:
Epithelial Biology and Secretion
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836133/
https://ncbi.nlm.nih.gov/pubmed/26867563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00210.2015
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