Increased susceptibility of Cftr(−/−) mice to LPS-induced lung remodeling

Cystic fibrosis (CF) is caused by homozygous mutations of the CF transmembrane conductance regulator (CFTR) Cl(−) channel, which result in chronic pulmonary infection and inflammation, the major cause of morbidity and mortality. Although these processes are clearly related to each other, each is lik...

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Vydáno v:Am J Physiol Lung Cell Mol Physiol
Hlavní autoři: Bruscia, Emanuela M., Zhang, Ping-Xia, Barone, Christina, Scholte, Bob J., Homer, Robert, Krause, Diane S., Egan, Marie E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836110/
https://ncbi.nlm.nih.gov/pubmed/26851259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00284.2015
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