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Attenuation of airway smooth muscle contractility via flavonol-mediated inhibition of phospholipase-Cβ

Enhanced contractility of airway smooth muscle (ASM) is a major pathophysiological characteristic of asthma. Expanding the therapeutic armamentarium beyond β-agonists that target ASM hypercontractility would substantially improve treatment options. Recent studies have identified naturally occurring...

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Brown, Amy, Danielsson, Jennifer, Townsend, Elizabeth A., Zhang, Yi, Perez-Zoghbi, Jose F., Emala, Charles W., Gallos, George
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836109/
https://ncbi.nlm.nih.gov/pubmed/26773068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00215.2015
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