The BECN1 N-terminal domain is intrinsically disordered

BECN1/Beclin 1 has a critical role in the early stages of autophagosome formation. Recently, structures of its central and C-terminal domains were reported, however, little structural information is available on the N-terminal domain, comprising a third of the protein. This lack of structural inform...

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Bibliographische Detailangaben
Veröffentlicht in:Autophagy
Hauptverfasser: Lee, Erinna F., Perugini, Matthew A., Pettikiriarachchi, Anne, Evangelista, Marco, Keizer, David W., Yao, Shenggen, Fairlie, W. Douglas
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2016
Schlagworte:
Basic Brief Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836020/
https://ncbi.nlm.nih.gov/pubmed/27046249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2016.1140292
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