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AMPK-dependent phosphorylation of lipid droplet protein PLIN2 triggers its degradation by CMA

Lipids stored in lipid droplets are hydrolyzed via either cytosolic lipases or a selective form of macroautophagy known as lipophagy. We recently demonstrated that chaperone-mediated autophagy (CMA) is required for the initiation of lipolysis by either of these independent lipolytic pathways. CMA se...

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Vydáno v:Autophagy
Hlavní autoři: Kaushik, Susmita, Cuervo, Ana Maria
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4835968/
https://ncbi.nlm.nih.gov/pubmed/26902588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1124226
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