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Degradation of lipid droplet-associated proteins by chaperone-mediated autophagy facilitates lipolysis
Chaperone-mediated autophagy (CMA) selectively degrades a subset of cytosolic proteins in lysosomes. A potent physiological activator of CMA is nutrient deprivation, a condition in which intracellular triglyceride stores or lipid droplets (LD) also undergo hydrolysis (lipolysis) to generate free fat...
Shranjeno v:
| izdano v: | Nat Cell Biol |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4449813/ https://ncbi.nlm.nih.gov/pubmed/25961502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3166 |
| Oznake: |
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