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Degradation of lipid droplet-associated proteins by chaperone-mediated autophagy facilitates lipolysis

Chaperone-mediated autophagy (CMA) selectively degrades a subset of cytosolic proteins in lysosomes. A potent physiological activator of CMA is nutrient deprivation, a condition in which intracellular triglyceride stores or lipid droplets (LD) also undergo hydrolysis (lipolysis) to generate free fat...

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Bibliografiska uppgifter
I publikationen:Nat Cell Biol
Huvudupphovsmän: Kaushik, Susmita, Cuervo, Ana Maria
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4449813/
https://ncbi.nlm.nih.gov/pubmed/25961502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3166
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