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Linking F-box protein 7 and parkin to neuronal degeneration in Parkinson’s disease (PD)
Mutations of F-box protein 7 (FBXO7) and Parkin, two proteins in ubiquitin-proteasome system (UPS), are both implicated in pathogenesis of dopamine (DA) neuron degeneration in Parkinson’s disease (PD). Parkin is a HECT/RING hybrid ligase that physically receives ubiquitin on its catalytic centre and...
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| Publicado no: | Mol Brain |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4835861/ https://ncbi.nlm.nih.gov/pubmed/27090516 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-016-0218-2 |
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