The histone deacetylase inhibitor PCI-24781 as a putative radiosensitizer in pediatric glioblastoma cell lines

BACKGROUND: Glioblastoma (GBM) is considered to be one of the most aggressive tumors of the central nervous system (CNS). Even with the use of modern treatment protocols, the prognosis remains reserved, with children with GBM having a mean survival of 12–15 months. METHODS: In the present study we i...

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Publicat a:Cancer Cell Int
Autors principals: de Andrade, Pamela Viani, Andrade, Augusto Faria, de Paula Queiroz, Rosane Gomes, Scrideli, Carlos Alberto, Tone, Luiz Gonzaga, Valera, Elvis Terci
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
Matèries:
Primary Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4835828/
https://ncbi.nlm.nih.gov/pubmed/27095947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-016-0306-5
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