HISTONE DEACETYLASE INHIBITOR PCI-24781 SHOWS ANTIPROLIFERATIVE EFFECTS AGAINST PEDIATRIC GLIOBLASTOMA CELLS

BACKGROUND: Glioblastoma (GBM) is one of the most aggressive tumors affecting the central nervous system (CNS). Despite combined aggressive treatment schedules, the prognosis of children with GBM remains very poor. Epigenetic mechanisms may interfere with the process of carcinogenesis, and the acety...

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Main Authors: Valera, Elvis Terci, Andrade, P.V., Andradre, A.F., Queiroz, R.G. de Paula, Scrideli, C.A., Tone, LG.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144576/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou208.30
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